Does TMAO *cause* Heart Disease? | Kevin Klatt PhD RD

Is TMAO a cause of heart disease or an innocent bystander? What is TMAO and what foods raise it? Should we avoid foods high in TMAO (or foods that raise TMAO levels)?Uploaded 10-06-24Connect with me:Facebook: https://www.facebook.com/DrGilCarvalho/Twitter: https://twitter.com/NutritionMadeS3Animations: Even Topland @toplandmediaReferences:TMAO production from choline and carnitine:https://www.mdpi.com/2072-6643/12/5/1330TMAO and risk of disease:https://link.springer.com/article/10.1007/s11883-021-00910-xhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7975634/TMAO genetics (mendelian randomization):https://www.sciencedirect.com/science/article/pii/S2161831323014515https://www.mdpi.com/1422-0067/24/3/1940What fraction of TMAO level is explained by diet?https://onlinelibrary.wiley.com/doi/abs/10.1002/mnfr.201700363TMAO and microbiome:https://www.nature.com/articles/nm.3145.TMAO, whole grains and fish:https://www.sciencedirect.com/science/article/pii/S0002916522004634Disclaimer: The contents of this video are for informational purposes only and are not intended to be medical advice, diagnosis, or treatment, nor to replace medical care. The information presented herein is accurate and conforms to the available scientific evidence to the best of the author's knowledge as of the time of posting. Always seek the advice of your physician or other qualified health provider with any questions regarding any medical condition. Never disregard professional medical advice or delay seeking it because of information contained in Nutrition Made Simple!.#NutritionMadeSimple #GilCarvalho0:00 What is TMAO?1:35 Cause or innocent bystander?3:22 Randomized trials4:16 Genetics5:37 TMAO levels7:14 Observational studies10:37 Diet vs endogenous production12:04 Whole grains and fish15:42 Individual nutrients19:25 Small effects Learn more about your ad choices. Visit megaphone.fm/adchoices
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