Gut Toxin's Hidden Door Found: Claudin-4 and Colon Cancer | Science Made Simple

Discover how Johns Hopkins scientists found claudin-4, the docking protein a gut bacterium's toxin needs before it can damage the colon lining. Learn how Bacteroides fragilis toxin BFT cuts E-cadherin, how a soluble claudin-4 decoy protected mice from toxin damage, and why this is not yet a human treatment or proven cancer prevention.

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