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Core IM | Internal Medicine Podcast

Core IM | Internal Medicine Podcast

#195 Antibiotic Duration & BALANCE Trial: Beyond Journal Club with NEJM Group

Core IM | Internal Medicine Podcast · Dec 10, 2025 · 21:44

0:0021:44

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Antibiotic duration for bacteremia is something most of us learned by habit, not by trial data. In this episode, we walk through the BALANCE trial and use it as a lens to revisit how 1) host, 2) organism, and 3) source should guide treatment. When shorter really is enough, and when it isn’t?

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🔹 Transcript and Shownotes

Timestamp

(02:58) | Host, Organism, Source: The Core Framework Behind Duration

(09:02) | How Evidence Shifted Practice

(11:27) | The BALANCE Trial: Short-Course vs Standard-Course Therapy

(18:55) | Where does this leave us?


Tags: CoreIM, Internal Medicine, Infectious disease, Evidence-Based Medicine, Clinical Reasoning, Hospital Medicine, Medical Education



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Episodes: Core IM | Internal Medicine Podcast

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