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Physique Development Podcast

Physique Development Podcast

What To Do When Your Labs Look "Normal" But You Still Feel Off (understanding progesterone & estradiol) | PD Podcast Ep.262

Physique Development Podcast · Mar 23, 2026 · 15:31

0:0015:31

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In the last episode, Coach Alex broke down how estrogen actually leaves the body. Today, he takes it one layer deeper. Because even when estrogen is clearing properly, you can still feel off—dealing with mood swings, poor sleep, anxiety, and cycles that feel like they're working against you... All while your labs come back "normal."


This is where the conversation shifts. Because "normal" on paper and optimal in the body are not the same, and the missing piece is often how we're looking at hormones. Most approaches isolate them, instead of understanding how they interact.


Alex dives into estrogen regulation—how hormones communicate, why symptoms can persist despite "normal" labs, and what your body is actually responding to beneath the surface. Because your hormones aren't broken, they're simply responding to the signals they're receiving.


Have questions for future episodes or a topic you'd like us to cover? Submit them here - https://forms.gle/AEu5vMKNLDfmc24M7


As always, it is our goal not only to supply you, the listener, with valuable insights on the topics or questions but also to plant some seeds for further research and thought. Be sure to like and subscribe and leave us a review wherever you're listening if you loved this episode!


Timestamps:

(0:00) Today's topic

(1:17) The problem with normal hormone panels

(2:54) What these hormones do in the body

(6:43) The things we should ACTUALLY be looking for

(7:34) Where we want the ratio to be

(9:06) Why this ratio is so important

(9:40) The main causes of suppressed ovulation quality

(11:11) The negative effects of low progesterone

(12:50) How we can start to fix this

(14:41) The most important takeaway & your next steps


The REAL Reason Your Estrogen Won't Go Down - https://pod.fo/e/3abc66


OPTIMIZE Your Muscle-Building:

Why You're Not Building Muscle Even Though You Lift Weights - https://pod.fo/e/3542c6

Why You DON'T Need a Huge Surplus to Build Muscle - https://pod.fo/e/358b03

How to Build Muscle While MINIMIZING Fat Gain (Part 1) - https://pod.fo/e/35d759

How to Build Muscle While MINIMIZING Fat Gain (Part 2) - https://pod.fo/e/361fc8

How Long Should a Muscle‑Building Phase Really Last? - https://pod.fo/e/366a56


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Coach Alex - https://www.instagram.com/alexbush__

Coach Sue - https://www.instagram.com/suegainz

Physique Development - https://www.instagram.com/physiquedevelopment_

Physique Development Podcast - https://www.instagram.com/physiquedevelopmentpodcast


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Produced by: David Margittai | In Post Media

Website: https://www.inpostmedia.com

Email: david@inpostmedia.com


© 2026, Physique Development LLC. All rights reserved.

Episodes: Physique Development Podcast

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