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In this Presidential Lecture, AlQuraishi will discuss recent evidence on the extent to which AlphaFold appears to learn to perform implicit physical modeling, and how this knowledge is acquired during its training. He will present use cases in which this implicit knowledge unlocks new capabilities and where it falls short. He also plans to discuss the differences between AlphaFold 2 and AlphaFold 3 regarding this question of implicit physical knowledge, and how their architectural differences may have led to different inductive priors.Uploaded 05-10-26For more information please visit: https://www.simonsfoundation.org/event/how-and-what-does-alphafold-learn-about-protein-structure/ Learn more about your ad choices. Visit megaphone.fm/adchoices