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Physician in the Loop

Physician in the Loop

Daily Briefing for October 23, 2026

Physician in the Loop · Oct 23, 2026 · 5:27

0:005:27

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Microsoft diagnostic AI beats generalist physicians on hard cases, study says

The voices on this episode are generated, and so is the script, from the day's post at Physician in the Loop. Every fact in the post links to its source.

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Microsoft's multi-agent diagnostic system reached the correct diagnosis in 83.2% of complex New England Journal of Medicine cases, against 36.1% for generalist physicians, in a benchmark study Science published online Oct. 22.

The physicians in the comparison were primary care physicians and general internists working alone with reference materials, and no specialists or physician teams took part, TechCrunch reported. The authors described the results as coming from a controlled benchmark, and Microsoft said it plans a prospective study at Beth Israel Deaconess Medical Center in Boston in which patients interact with the system directly.

Elsewhere, the director of the Food and Drug Administration's Digital Health Center of Excellence said Oct. 20 that draft guidance on generative AI devices will come in the coming months, MedTech Dive reported. Sutter Health said more than 6,000 of its clinicians have drafted more than 5 million notes with Abridge's ambient AI, and the FDA approved Edwards Lifesciences' Pascal Precision system for transcatheter repair of the tricuspid valve.

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