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Physician in the Loop

Physician in the Loop

Daily Briefing for November 11, 2026

Physician in the Loop · Nov 11, 2026 · 5:51

0:005:51

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FDA adds vision-loss warning to every GLP-1 drug, from Ozempic to Zepbound

The voices on this episode are generated, and so is the script, from the day's post at Physician in the Loop. Every fact in the post links to its source.

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The Food and Drug Administration on Nov. 9 ordered a warning about nonarteritic anterior ischemic optic neuropathy, a rare cause of sudden vision loss, added to the labels of every GLP-1 receptor agonist.

The change covers semaglutide, tirzepatide, liraglutide, dulaglutide, the oral drug orforglipron and generic exenatide. In a meta-analysis of 126 randomized trials, the agency counted 6.4 cases per 100,000 person-years with the drugs and 3.8 with comparators; in its Sentinel cohort, the hazard ratio against DPP-4 inhibitors was 1.43.

Google Cloud opened a preview of an AI agent that works across hospitals' records and billing systems, with HCA Healthcare, Highmark Health and Northwell Health as launch partners. An international commission began a four-day review of whether the United States still meets the definition of measles elimination, and the FDA warned that connectors on some ventilator breathing tubes can detach.

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