DeepMind's AlphaGenome 2 Predicts Variant Effects Cell by Cell

Google DeepMind's AlphaGenome 2 predicts variant effects cell by cell
Databricks pitches Genie as an always-on agent that works unsupervised
Startup PSI says early access to Anthropic's Fable 5.2 solved an 18-year quantum conjecture

A Eye on AI - 12:31 PM
Google DeepMind's AlphaGenome 2 leads today's briefing: a DNA model trained on more than 100 million individual cell profiles across 68 tissues, which DeepMind says flags nearly twice as many gene-expression variants as its previous model, and is now available for non-commercial research through an API. Then Databricks updates its Genie agent, with CEO Ali Ghodsi showing how he uses it to surface bad news inside a 12,000-person company. We also cover the startup PSI, which says researcher David Turturean used early access to Anthropic's Fable 5.2 to solve an 18-year-old quantum computing conjecture that Scott Aaronson calls likely correct. Plus OpenAI's beta Business Hub and Business Agents inside ChatGPT, and why New York's RAISE Act registration portal matters for frontier AI developers like Anthropic and OpenAI under Governor Kathy Hochul, ahead of a January 1, 2027 start.

Sources:
- TechCrunch AI: https://techcrunch.com/2026/11/11/databricks-new-ai-agent-tells-ceo-ali-ghodsi-the-unvarnished-truth/
- TechCrunch AI: https://techcrunch.com/2026/11/10/openai-anthropic-face-new-oversight-as-new-yorks-ai-safety-law-takes-effect/
- TechCrunch AI: https://techcrunch.com/2026/11/10/psi-is-trying-to-make-a-business-out-of-ai-driven-scientific-discovery/
- TechCrunch AI: https://techcrunch.com/2026/11/10/openai-rolls-out-new-business-profiles-making-chatgpt-just-a-little-bit-more-like-google/
- The Verge AI: https://www.theverge.com/ai-artificial-intelligence/1030552/openai-chatgpt-business-agents-hub
- MarkTechPost: https://www.marktechpost.com/2026/11/10/ifm-pan-2-open-world-model/
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- Google AI Blog: https://blog.google/products-and-platforms/platforms/android/gemini-intelligence-november-features-devices/
- Google DeepMind Blog: https://deepmind.google/blog/alphagenome-2-deciphering-how-cells-read-dna-to-better-understand-disease/
- The Verge AI: https://www.theverge.com/ai-artificial-intelligence/1031524/google-deepmind-alphagenome-2-genetic-ai-model
- The Verge AI: https://www.theverge.com/tech/1031526/google-tabletop-ai-experiment-waitlist-availability
- auganix.org: https://www.auganix.org/xr-news-google-genie-4-world-model/
- The Verge AI: https://www.theverge.com/tech/1031505/adobe-max-2026-sneaks-experiments-ai
- Hugging Face Blog: https://huggingface.co/blog/qvac/botpsy
- Hugging Face Blog: https://huggingface.co/blog/token-pooling
- unite.ai: https://www.unite.ai/anthropic-announces-claude-meetings-with-a-google-meet-whiteboard-beta/
- Reddit r/LocalLLaMA: https://www.reddit.com/r/LocalLLaMA/comments/1xtmeif/open_source_self_driving_is_here/
- Reddit r/LocalLLaMA: https://www.reddit.com/r/LocalLLaMA/comments/1xtmcoe/unsloth_dynamic_v31_released_for_qwen3827b/
- Reddit r/LocalLLaMA: https://www.reddit.com/r/LocalLLaMA/comments/1xtmbkn/kraftonraon1nano_hugging_face/

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