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COVID-19 Mortality Risk Correlates Inversely with Vitamin D3 Status, Uploaded 17-11-21a Mortality Rate Close to Zero Could Theoretically Be Achieved at 50 ng/mL 25(OH)D3: (125 nmol/L)Results of a Systematic Review and Meta-Analysishttps://www.mdpi.com/2072-6643/13/10/3596Blood calcifediol (25(OH)D3) levels correlate strongly with SARS-CoV-2 infection severityCause or effect?Strength of our immune system,More or less neglected by the responsible authoritiesNutrition, physical fitness, recreation, sleepWidespread vitamin D deficiencyData collected March 2021MethodsSystematic literature searchRetrospective cohort studies (1)Clinical studies (7) on COVID-19 mortality rates versus D3 blood levelsReported D3 blood levels pre-infection or on the day of hospital admissionMortality rates, corrected for age, sex, and diabetesResultsNegative Pearson correlation of D3 levels and mortality riskr = −0.4154, p = 0.0770r = −0.4886, p = 0.0646Combined dataMedian D3 levels were 23.2 ng/mL (58 nmol/L)Pearson correlation = −0.3989, p = 0.0194Regression suggested a theoretical point of zero mortality at approximately 50 ng/mL (125 nmol/L) D3ConclusionsThe datasets provide strong evidence that low D3 is a predictor rather than just a side effect of the infection. Despite ongoing vaccinations, we recommend raising serum 25(OH)D levels to above 50 ng/mL Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices
