Mayo Clinic Talks · May 5, 2026 · 30:30
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Host: Darryl S. Chutka, M.D.
Guest: Uma Thanarajasingham, M.D., Ph.D.
Systemic lupus is a chronic autoimmune disease with a variety of immunologic and laboratory abnormalities. It has numerous clinical manifestations potentially involving multiple organs. It’s known as the great imitator because it can mimic a variety of other diseases, and it’s not uncommon for patients to have symptoms for a number of years prior to a diagnosis being established. What symptoms should alert us to the possibility of lupus? What do we do with a low titer, positive ANA? How is a firm diagnosis established and what role does the primary care clinician play in the management of those with lupus? I’ll be asking these questions and more of my guest, Dr. Uma Thanarajasingam from the Division of Rheumatology at the Mayo Clinic as we discuss “Lupus Today: Advances in Diagnosis and Treatment”.
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