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Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

Ep. 584 "Slowing the Engine” – How GLP-1s Alter Your Gut Motility & Microbiome | Menopause, Perimenopause & Gut Health

Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+ · Apr 23, 2026 · 21:13

0:0021:13

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Welcome to today’s Midlife Minute.

In this episode, I answer listeners’ questions about GLP-1 medications and midlife weight changes. I explore how hormonal shifts, insulin sensitivity, muscle mass, and the gut microbiome influence the effectiveness of these drugs, and explain why they should be regarded as part of a broader metabolic and lifestyle framework.

IN THIS EPISODE, YOU WILL LEARN:



Why GLP-1 medications don’t necessarily fix the root cause of midlife weight gain 




How declining estrogen can disrupt your appetite and satiety hormones




The value of checking your fasting insulin to understand your insulin sensitivity level




How inadequate protein can cause cravings for processed carbohydrates and fats




Why preserving muscle mass is critical to prevent sarcopenic obesity  




How GLP-1 medications affect digestion and gut motility




The clinical factors that are considered when prescribing GLP-1 medications 




Some simple daily habits to support your metabolic and microbiome health when using GLP-1 medications 




Connect with Cynthia Thurlow  



Follow on X, Instagram & LinkedIn




Check out Cynthia’s website




Submit your questions to support@cynthiathurlow.com




Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow 




Cynthia’s Menopause Gut Book is on presale now!




Cynthia’s Intermittent Fasting Transformation Book




The Midlife Pause Supplement Line

Episodes: Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

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