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Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

Ep. 637 HRT Dosing: Absorption, Timing, and Lab Testing |Menopause, Perimenopause, Hormone Replacement Therapy

Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+ · Sep 3, 2026 · 16:31

0:0016:31

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Welcome to this week’s Midlife Minute episode.

Today, we’re diving into listener questions about HRT dosing and the confusion surrounding administration. We explore several key themes, including absorption issues, lab draws, and cycling versus daily continuous dosing. I also compare oral progesterone with vaginal and transdermal progesterone.

Stay tuned for more!

IN THIS EPISODE, YOU WILL LEARN:


The estradiol dosage range I prefer, for bone protection



How heart disease risk can influence the route you select for HRT



I clarify the “start low and slow” approach to HRT dosing



Why women with uteruses need progesterone when taking estrogen 



Why HRT dosing can become more complicated during perimenopause



How FDA-approved bioidentical hormones differ from compounded preparations



Various factors to consider when using an estradiol patch



Alternative routes of administration for women who feel unwell when taking progesterone orally



How providers can safely transition women from transdermal estradiol patches to other options




Connect with Cynthia Thurlow  


Follow on X, Instagram & LinkedIn



Check out Cynthia’s website.



Submit your questions to support@cynthiathurlow.com 



Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow. 



Purchase Cynthia’s book, The Menopause Gut.



Cynthia’s Intermittent Fasting Transformation Book



The Midlife Pause Supplement Line




Research:

Please visit https://www.cynthiathurlow.com/podcast for research.

Episodes: Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

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