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Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

Ep. 650 ADHD and Hormones in Women with Dr. Jolene Brighten

Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+ · Oct 3, 2026 · 1:00:25

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Today, I’m honored to reconnect with Dr. Jolene Brighten. She’s an award-winning, board-certified naturopathic endocrinologist, nutrition scientist, and leading voice in women’s health. She’s the author of Beyond the Pill, Healing Your Body Naturally After Childbirth, and her latest book, ADHD and Women: A Guide to Optimizing Your Hormones and Thriving with ADHD, which represents an expansion of her core thesis that women’s symptoms get chronically misattributed when the hormone piece is left out of the picture, which she now applies to ADHD. She also hosts The Dr. Brighten Show.

In today’s conversation, we look at why ADHD symptoms surface or worsen at hormonal transitions, the mental health effects of oral contraceptives and synthetic hormones, and the gut-brain connection to ADHD. We explore how gut dysbiosis dysregulates vagal nerve signaling; how butyrate and other short-chain fatty acids influence it; what endobelly is and how it affects histamine and mast cell degranulation; and emerging research on GLP-1s and endometriosis. We also discuss rejection sensitivity disorder and masking, nutritional and o lifestyle recommendations for improving symptomatology, and how key supplements like cytochrome and saffron can improve memory and mitochondrial health.

Stay tuned for a truly insightful conversation with Dr. Jolene Brighten and a deeper look at ADHD and Women.

IN THIS EPISODE, YOU WILL LEARN:


How perimenopause can amplify ADHD symptoms



Why ADHD in some women remains unidentified until midlife



How gut dysbiosis can influence vagal nerve signaling in the ADHD brain



Why butyrate and resistant starches may be important for the ADHD brain



The connection between endometriosis, ADHD, and the gut



How Dr. Brighten guides neurodivergent women through HRT conversations 



How rejection sensitivity dysphoria can affect women with ADHD



Dr. Brighten shares lifestyle recommendations for women with ADHD




Bio: 

Dr. Jolene Brighten is a hormone expert, nutrition scientist, and founder of Dr. Brighten Essentials. Board-certified in naturopathic endocrinology, a certified menopause specialist, and sex counselor, she is the bestselling author of Beyond the Pill, Is This Normal?, and the forthcoming ADHD and Women. She is dedicated to helping women optimize their hormone, brain, and sexual health through evidence-based education.

Connect with Cynthia Thurlow  

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Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow. 

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Connect with Dr. Jolene Brighten

Website

Pre-order bonuses for ADHD and Women (Meal plans to help optimize hormones and a PMDD workshop)

On Social Media: @DrJoleneBrighten

The Dr. Brighten Show

Episodes: Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

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