52. Advanced Fertility Testing Before IUI or IVF: Everything You Need to Know About Male and Female Fertility Tests

Advanced Fertility Testing Before IUI or IVF: Everything You Need to Know About Male and Female Fertility Tests

Episode 52   |   Her Fertility Podcast   |   Fertility Journey Series

 

Episode Overview

Before your doctor can recommend IUI or IVF, there's a set of advanced fertility tests that build the picture of what's actually happening in your body. In this episode of the Fertility Journey Series, Jess Tims walks through every test you're likely to encounter — for both the male and female partner — explaining what each one measures, how it's done, and what to make of the results. Jess also shares her own emotional experience with the HSG exam, and why preparing yourself emotionally for these appointments matters just as much as preparing physically.

"You don't want to waste any more time just because you don't know something. Ask. Ask your practitioner, ask about your insurance coverage, ask what comes next. Knowledge is how you advocate for yourself." — Jess Tims

What You'll Learn in This Episode

• The advanced fertility tests typically prescribed before IUI or IVF — for both partners
• What a semen analysis measures: sperm count, motility, and morphology — and why all three matter
• What DNA fragmentation testing is and why Jess recommends it if it's available to you
• How the female hormone panel works and why it's often done in two parts across your cycle
• What AMH (anti-Müllerian hormone) is, what it estimates, and its important limitations
• What the HSG exam is, how the procedure works, and why it's typically required before IUI or IVF
• Jess's personal experience with the HSG — including what she wishes she had known beforehand
• Why emotional preparation for fertility testing is as important as physical preparation
• How to use test results alongside your inner guidance to make the best decision for your journey

 

The Tests at a Glance

Test

What it measures

Who it applies to

Semen analysis

Sperm count, motility (movement), and morphology (shape)

Male partner

DNA fragmentation

DNA abnormalities in sperm that could affect embryo development

Male partner (optional add-on)

Hormone panel

Reproductive hormone levels; progesterone tested separately in the luteal phase (around day 20)

Female partner

AMH test

Estimated ovarian reserve (egg count) via anti-Mullerian hormone level

Female partner

HSG exam

Whether fallopian tubes are open or blocked (using dye and imaging)

Female partner (typically required before IUI/IVF)

 

Male Fertility Testing

Semen analysis

A semen analysis is painless, non-invasive, and yields a significant amount of data. It can be ordered through your primary care physician, via a specialist referral, or done at home through services like Legacy (discount link in the show notes). The analysis measures:

• Sperm count — the total number of sperm in the sample
• Motility — how the sperm are moving (stationary sperm can't reach the egg)
• Morphology — the shape of the sperm. Because the egg is the strongest cell in the female body, it takes a healthy, well-formed sperm to break through and fertilize it

DNA fragmentation analysis

An optional but valuable add-on to the standard semen analysis. This test examines the DNA makeup of the sperm for abnormalities that could affect embryo development — issues that wouldn't show up in a standard analysis. Jess recommends requesting this if it's accessible to you.

Female Fertility Testing

Advanced hormone panel (blood test)

This blood test measures your reproductive hormone levels. Many practitioners split it across two points in your cycle:

• Cycle days 1–3 (during your period): hormones are at their baseline, giving a clear resting reading
• Around day 20 (luteal phase): progesterone is tested here because this is when levels are highest and most meaningful

Coverage and protocols vary by practitioner and insurance provider. Ask your provider exactly which hormones they're testing and when, so you're not missing key data.

AMH test (anti-Müllerian hormone)

AMH is secreted by the follicles inside your ovaries. Your practitioner measures it via blood test to estimate your ovarian reserve — how many follicles you have remaining. Key things to understand about your AMH result:

• It is a point-in-time reading — AMH levels can change as your overall health changes
• It estimates quantity, not quality. There is currently no test that can directly measure egg quality
• It is measured relative to your age — what's considered 'normal' shifts across different life stages
• An exact egg count is not possible with current technology; AMH is the best available estimate

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