Ole Miss, Pete Golding UPSET Alert is Real vs Louisville--Jeff Brohm Seeks STATEMENT for ACC vs SEC

Ole Miss vs Louisville is one of the biggest games of Week 1, but is sadly a neutral site game. The Rebels are on serious upset alert this weekend.

On today's episode of Locked On College Football, Spencer McLaughlin and 'Locked On Buffs' host Kevin Borba discuss Colorado's Thursday matchup at Georgia Tech. How can the Buffs pull the upset?

The Big 10 enters 2026 looking to win its 4th straight national championship. Who wins the conference, who is a darkhorse, and who finishes in last place?

Photo Credit: Nathan Ray Seebeck-Imagn Images

00:00 Louisville's coaching and quarterback potential

06:16 Pressuring opposing quarterbacks

07:01 Ole Miss vs. Louisville strategy

12:55 Predicting Colorado vs. Georgia Tech Game

14:25 Colorado's new recruitment strategy

17:45 Impact of Great Coaching in College Football

24:19 Big Ten football predictions

28:46 Big Ten dark horse pick

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