Why Nausea & Migraines Are Linked Through the Gut-Brain Axis

Why do so many migraine attacks come with nausea, bloating, stomach discomfort, or digestive shutdown?

In this episode of The Migraine Heroes Podcast, host Diane Ducarme explores the powerful connection between migraines and the gut-brain axis. Blending neuroscience with holistic healing perspectives, this episode reveals why nausea is not “just a symptom,” but often part of the migraine process itself.

You’ll discover:

💡 Why nausea is deeply connected to the migraine process — not simply a secondary side effect

💡 How the gut-brain axis can increase inflammation, stress signaling, and nervous system overload during attacks

💡 Simple ways to calm your digestive system at home that may help reduce migraine-related nausea naturally

If you’ve ever felt like your stomach and brain are reacting together during migraines, this episode will help you better understand the deeper connection behind your symptoms.

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References:

• Pathophysiology of Migraine (Goadsby et al., 2017): This review explains migraine as a disorder of sensory processing involving trigeminovascular pathways, altered brain excitability, and brainstem dysfunction. Read more here .
• Gut Microbiota and Migraine (related alternative): This review explains how microbiota-mediated gut–brain crosstalk may contribute to migraine pathophysiology. Read more here .
• Gastric Stasis in Migraine (Aurora et al., 2006): This paper examines delayed gastric emptying in migraine patients during and between attacks. Read more here .
• The CGRP Pathway in Migraine (Edvinsson, 2018): This paper reviews CGRP as a key migraine pathway and therapeutic target. Read more here .
• Gut Feelings: Gut–Brain Communication (Mayer, 2011): This review explores bidirectional communication between the gut and brain, including effects on digestion, emotion, motivation, and higher cognitive functions. Read more here .

Disclaimer: This podcast is for informational purposes only and does not substitute for providing medical advice. Always consult your healthcare professional before making any health-related decisions.

For women, men, and children who suffer from migraine disease, Migraine Heroes is your go-to resource for understanding, managing, and overcoming migraine attacks.

We cover all types of migraines and related headaches, including primary and secondary migraines, chronic migraines, and cluster migraines. We dive deep into the complexities of migraine with aura and migraine without aura, as well as rarer forms like hemiplegic migraine, retinal migraine, and acephalgic migraine (silent migraine). Our discussions also extend to cervicogenic headaches, ice pick headaches, and pressure headaches, which often mimic migraine or contribute to overall migraine burden.