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The Occupational Safety Leadership Podcast

The Occupational Safety Leadership Podcast

Measuring Worker Fatigue with James Walsh of Hyperion Biotechnology-part1

The Occupational Safety Leadership Podcast · Jun 27, 2026 · 32:02

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Fatigue contributes to accidents, now there's an accurate test.  This is part 1 of fatigue testing using non-invasive saliva chews with James Walsh. Hyperion Biotechnology developed a non‑invasive saliva‑based test that measures biological markers linked to fatigue, stress, and readiness for duty. The goal is to give employers an objective way to identify when workers may be too fatigued to perform safely — especially in high‑risk environments.

Guest information - James Walsh https://www.linkedin.com/in/james-walsh-675193129/ 

Hyperion Biotechnology - https://hyperionbiotechnology.com/ 

  🔬 1. What the Test Measures

What is measured is a proprietary, patented biomarker for fatigue. It’s not cortisol. The peptide ratio I describe is the Fatigue Biomarker Index is a biomarker assay that is exclusive to Hyperion (that we developed with the Army and Air Force).

  🧪 2. How the Test Works

This creates an objective fatigue score, rather than relying solely on self‑reporting or supervisor observation.

  🛡️ 3. Why It Matters for Occupational Safety

Fatigue is a major contributor to:

Hyperion’s test gives safety leaders a data‑driven tool to identify fatigue before it leads to incidents — especially in:

Employees receive a personalized report with strategies to help reduce their fatigue.   📌 Key Takeaways for Safety Leaders

Episodes: The Occupational Safety Leadership Podcast

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