Aspirin Plus Anticoagulation: What Are the Risks? - Frankly Speaking Ep 465

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-465

Overview: Many patients with coronary artery disease take aspirin, but how should clinicians navigate management when an anticoagulant is also needed? In this episode, we review indications for therapy, explore evidence on dual use, and discuss how to counsel patients on balancing cardiovascular benefits with the risks of combination therapy.

Episode resource links:

• Lemesle G, Didier R, Steg PG, et al. Aspirin in Patients with Chronic Coronary Syndrome Receiving Oral Anticoagulation. N Engl J Med. Published online August 31, 2025.

  https://www.nejm.org/doi/full/10.1056/NEJMoa2507532

Guest: Alan M. Ehrlich, MD, FAAFP   Music Credit: Matthew Bugos

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