Optimal Protein Podcast with Vanessa Spina
Optimal Protein Podcast with Vanessa Spina · Dec 15, 2025 · 1:00:52
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Why do so many people lose weight — only to regain it later?
In this episode of The Optimal Protein Podcast, Vanessa Spina sits down with Dr. Holly Wyatt, physician, endocrinologist, and longtime researcher with the National Weight Control Registry (NWCR) — the world's largest and longest-running study of people who have lost weight and kept it off.
Building on the audience-favorite episode with Dr. James Hill, this conversation focuses on what the data from over 10,000 successful maintainers actually shows — and why staying in fat-loss mode forever is one of the biggest reasons diets fail.
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In This Episode, You'll Learn:
• Why losing weight and keeping it off require completely different skills
• The exact reason staying in fat-loss mode too long backfires
• What 10,000 successful maintainers had in common
• The identity shift that makes maintenance stick
• How environment beats willpower every time
NEW! Free High-Protein Keto Guide
Get delicious high protein meal recipes! Connect with Vanessa on Instagram @ketogenicgirl
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The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.
Episodes: Optimal Protein Podcast with Vanessa Spina