The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!
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Sep 29, 2026 · 51:27
a16z General Partner Anish Acharya sits down with Assistant Benchmark creator David Pawlan to unpack the sudden explosion of personal AI agents and what it will take for one to…
Sep 28, 2026 · 43:14
a16z’s Ben Horowitz and Martin Casado sit down with TypeSafe AI founder Diogo Almeida to ask a simple question: AI has become remarkably capable, so where is all the automation?…
Sep 27, 2026 · 48:08
a16z’s Katie Kirsch sits down with Harvey VP of Talent Maggie Landers to discuss what happens inside a company growing at AI speed, and how you preserve culture while adding more…
Sep 26, 2026 · 56:00
Erik Torenberg sits down with Box CEO Aaron Levie, and a16z’s Martin Casado, and Steven Sinofsky to debate how the AI industry should think about safety, security, and regulation…
Sep 25, 2026 · 50:23
a16z’s Erik Torenberg sits down with Josh Elman, Olivia Moore, and David Booth to introduce Cosign, a new product built around professional reputation and the people, companies,…
Sep 24, 2026 · 27:49
a16z crypto General Partner Eddy Lazzarin joins Theo Jaffee on MTS to debate the increasingly prominent calls to slow AI development and whether the current safety conversation…
Sep 23, 2026 · 47:47
Erik Torenberg sits down with Replit founder and CEO Amjad Masad and Horowitz and Andreessen Academy co-founder and CEO Gagan Biyani to ask what education should look like for a…
Sep 22, 2026 · 43:02
Ben Horowitz and Erik Torenberg sit down with Gagan Biyani to introduce the Horowitz and Andreessen Academy and discuss a bigger question: what should education look like when AI…
Sep 21, 2026 · 29:02
a16z Board Partner and former Microsoft Windows president Steven Sinofsky joins Theo Jaffee and Sofia Puccini on MTS to argue that the language we use to describe AI failures is…
Sep 20, 2026 · 57:18
Ben Horowitz and Erik Torenberg sit down with Nas, Grandmaster Caz, and Steve Stoute for a conversation about the Paid in Full Foundation and its mission to recognize and support…
Sep 19, 2026 · 1:00:18
a16z Partner Josh Elman joins Ollie Forsyth on New Economies to discuss the next wave of consumer AI and what separates a product people try once from one that becomes part of…
Sep 18, 2026 · 1:08:34
Databricks co-founder and CEO Ali Ghodsi joins a16z General Partners Martin Casado and Sarah Wang for a conversation about AI risk, recursive self-improvement, cybersecurity, and…
Sep 17, 2026 · 39:32
a16z General Partner Jennifer Li sits down with fal co-founder Gorkem Yurtseven and Head of Engineering Batuhan Taskaya to discuss what changes when generative video becomes fast…
Sep 16, 2026 · 52:43
a16z’s Alex Rampell and Joe Schmidt sit down with Lightfield co-founder and CEO Keith Peiris to discuss what it takes to rethink the CRM for an AI-native world, and the unusual…
Sep 15, 2026 · 42:39
Elena Burger sits down with academic and cyber ethnographer Ruby Justice Thelot to explore the increasingly blurry line between internet culture and the real world, and how to…
Sep 14, 2026 · 51:02
Ben Horowitz and Erik Torenberg sit down with OpenAI co-founder and President Greg Brockman to discuss why he believes AI has entered a new phase, what OpenAI’s latest models…
Sep 13, 2026 · 23:30
World Labs co-founder Justin Johnson joins MTS hosts Theo Jaffee and Sofia Puccini to discuss Atlas, World Labs’ latest world model, and the broader case for AI systems that…
Sep 12, 2026 · 1:18:04
a16z General Partner Anish Acharya joins Lenny Rachitsky on Lenny’s Podcast to discuss why fears of an AI-driven “permanent underclass” may be misplaced, how AI is changing the…
Sep 11, 2026 · 38:05
a16z’s Matt Perault sits down with General Partner and Speedrun lead Andrew Chen on the a16z AI Policy Brief to explore what “Little Tech” actually looks like at the earliest…
Sep 10, 2026 · 49:23
a16z’s Jen Kha and David George sit down with Accolade Partners’ Aram Verdiyan to discuss how AI is changing the power law of technology investing, why the largest companies can…
Sep 9, 2026 · 39:45
a16z’s Erik Torenberg, Ben Horowitz, and Jennifer Li sit down with Vals founder and CEO Rayan Krishnan to discuss one of AI’s increasingly difficult problems: how do you actually…
Sep 8, 2026 · 1:05:15
a16z Infra Partner Lisha Li sits down with OpenAI mathematicians Mehtaab Sawhney and Mark Sellke to discuss how quickly AI’s mathematical capabilities are advancing, what recent…
Sep 7, 2026 · 8:05
MTS host Sophia Dew visits the Open Source AI Summit in San Francisco to ask researchers and founders across the AI stack a central question: can open source prevent AI power…
Sep 6, 2026 · 27:30
a16z General Partner Julie Yoo joins MTS host Sophia Dew to explain why she believes healthcare could benefit more from AI than almost any other industry, and why decades of slow…
Sep 5, 2026 · 31:05
Box co-founder and CEO Aaron Levie joins MTS hosts Theo Jaffee and Sofia Puccini to make the case for open-weight AI, unpack the economics of open versus closed models, and…
Sep 4, 2026 · 44:36
World Labs co-founders Fei-Fei Li, Justin Johnson, and Ben Mildenhall join a16z General Partner Martin Casado to discuss Atlas, their latest world model, and what it reveals…
Sep 3, 2026 · 1:00:39
Erik Torenberg is joined by a16z General Partner Alex Rampell and Affirm Co-Founder and CEO Max Levchin for a conversation on 25 years of fintech, from the early days of digital…
Sep 2, 2026 · 40:10
a16z General Partner Jorge Conde sits down with Moderna CEO Stéphane Bancel to discuss a major milestone for mRNA technology: positive Phase 3 results from Moderna and Merck’s…
Sep 1, 2026 · 1:03:49
a16z’s Lisha Li sits down with Daniel Litt, Assistant Professor of Mathematics at the University of Toronto, to unpack AI's rapid progress in mathematics, what today's frontier…
Aug 31, 2026 · 1:15:11
a16z’s David George sits down with Gavin Baker to unpack the state of the AI boom, why demand for intelligence may still be dramatically underestimated, and why the outcome…
Aug 30, 2026 · 24:37
a16z Managing Partner and Head of Global Partnerships Jen Kha joins MTS hosts Theo Jaffee and Sophia Dew to discuss a16z's Machine Age Fund and the investment thesis behind…
Aug 29, 2026 · 34:15
Ryan Greenblatt, Chief Scientist at Redwood Research, joins MTS host Theo Jaffee to unpack a new independent investigation into the OpenAI Hugging Face hacking incident and what…
Aug 28, 2026 · 55:02
Ben Horowitz, Martin Casado, Raghu Raghuram, and Erik Torenberg discuss the launch of a16z's new Machine Age Fund and the infrastructure buildout behind AI, from chips, memory,…
Aug 27, 2026 · 39:29
a16z General Partners Martin Casado, Sarah Wang, and Matt Bornstein unpack the story of Cursor: how a small, product-obsessed team entered one of the most competitive markets in…
Aug 26, 2026 · 37:14
Anish Acharya joins Jen Kha to break down the next frontier of AI, from the evolving model landscape and open-source AI to why the application layer, and consumer AI in…
Aug 25, 2026 · 1:03:32
a16z General Partners Martin Casado and Erik Torenberg are joined by Board Partner Steven Sinofsky to explore what recent breakthroughs in AI and mathematics tell us about where…
Aug 24, 2026 · 35:21
Daisy Wolf and Eva Steinman are joined by Engy Ziedan, co-founder and Chief Scientific Officer of Protege, to discuss why medical AI has a measurement problem, and why scoring…
Aug 22, 2026 · 42:01
Martin Casado joins MTS hosts Theo Jaffee and Sophia Dew to unpack where value is actually accruing in AI, why this technology cycle looks fundamentally different from previous…
Aug 21, 2026 · 25:15
a16z's Joel De La Garza is joined by Aaron Zollman, Deputy CISO at Microsoft Gaming, to discuss how security teams can embrace AI agents without losing control. Aaron shares…
Aug 20, 2026 · 45:44
Elena Burger is joined by a16z’s Angela Strange and Gabriel Vasquez to discuss the rise of the "borderless founder": entrepreneurs who bring the networks and insights of their…
Aug 19, 2026 · 42:39
a16z General Partner David George is joined by Grant LaFontaine, co-founder of Whatnot, to unpack how a marketplace that started with collectibles evolved into one of the world's…
Aug 18, 2026 · 22:00
a16z's Joel De La Garza is joined by Nick Warner of Neo and Max Pollard of Cotool to discuss what happens when cybersecurity tools built to defend against humans and malware…
Aug 17, 2026 · 54:36
a16z General Partner David George is joined by Will Gaybrick, President of Product & Business at Stripe, to discuss how AI is changing the way Stripe builds products, organizes…
Aug 14, 2026 · 33:37
Ben Horowitz, Travis Kalanick, and Erik Torenberg take the stage at Atoms' launch event for a candid fireside conversation about entrepreneurship, company building, and why…
Aug 13, 2026 · 44:37
Elena Burger is joined by a16z's Andy McCall and Joe Schmidt to break down two very different ways AI startups can go to market: the lighthouse and the landgrab. Should founders…
Aug 12, 2026 · 52:03
Anish Acharya is joined by Garry Tan, President and CEO of Y Combinator, for a conversation about how AI is rewriting the startup playbook, why founders should be more ambitious…
Aug 11, 2026 · 22:54
a16z's Joel De La Garza is joined by Emilio Escobar, Chief Information Security Officer at Datadog, to discuss what it takes to secure a company where nearly every employee is…
Aug 10, 2026 · 37:20
Angela Strange and Gabriel Vasquez are joined by Alejandro Maza Ayala, Chief Product & AI Officer at Kavak, to unpack how the Latin American used-car marketplace rebuilt itself…
Aug 7, 2026 · 23:51
Joel De La Garza is joined by Dylan Ayrey, co-founder and CEO of Truffle Security, and Feross Aboukhadijeh, founder and CEO of Socket, to discuss one of the biggest shifts…
Aug 6, 2026 · 46:49
Elena Burger and Matt Bornstein are joined by Simon Mo, co-founder and CEO of Inferact, the open-source inference engine powering many of today's most advanced AI applications.…
Aug 5, 2026 · 1:15:22
This week, a16z American Dynamism Films premiered three short documentaries highlighting companies tackling some of America's biggest industrial challenges: Ulysses, Mariana…
Aug 4, 2026 · 31:09
Theo Jaffee is joined by Joshua Achiam, Chief Futurist at OpenAI, for a conversation on AI cybersecurity, frontier model capabilities, and why he believes society may have…
Aug 2, 2026 · 34:08
Sophia Dew and Sofia Puccini are joined by Ruby Thelot, designer, artist, cyberethnographer, professor at NYU, and founder of 13101401, for a wide-ranging conversation about…
Aug 1, 2026 · 59:55
Marc Andreessen, Chris Dixon, and Robert Hackett discuss one of the most consequential policy debates facing the crypto industry: the push for comprehensive U.S. market structure…
Jul 31, 2026 · 1:20:36
Sarah Wang and Kimberly Tan are joined by Jesse Zhang and Ashwin Sreenivas, co-founders of Decagon, to discuss the evolution of enterprise AI agents, why the company increasingly…
Jul 30, 2026 · 58:58
Alex Rampell and Olivia Moore speak with Lassie cofounders Steijn Pelle and Frédéric Renken about bringing AI to one of the most overlooked parts of the economy: small…
Jul 29, 2026 · 51:02
Justine Moore, partner at Andreessen Horowitz, joins New Economies to explore the rapid evolution of generative media and why AI-native content is reaching an inflection point.…
Jul 28, 2026 · 43:04
Last week, World Labs announced its acquisition of SceniX, bringing together two teams working on one of AI's biggest unsolved problems: how to give machines a true understanding…
Jul 27, 2026 · 29:16
Steven Sinofsky joins Theo Jaffee and Sofia Puccini for a conversation on AI regulation, open-source models, and what history can teach us about technological revolutions.…
Jul 26, 2026 · 32:35
Ben Horowitz joins Theo Jaffee and Sofia Puccini to discuss one of the biggest debates in AI today: the future of open-source models. They examine the growing push to restrict…
Jul 24, 2026 · 23:04
Sriram Krishnan joins Theo Jaffee and Sofia Puccini just after concluding his tenure as Senior White House Policy Advisor on AI to discuss one of the biggest weeks yet for…
Jul 23, 2026 · 45:25
Travis Kalanick joins TBPN to discuss Atoms, his vision for industrial AI, and why he believes the biggest opportunities in AI lie beyond software. He explains how Atoms is…
Jul 22, 2026 · 1:32:13
Travis Kalanick, Ben Horowitz, and Erik Torenberg reunite to reflect on Uber's early days, the investment that almost happened, and why Kalanick believes the next great…
Jul 21, 2026 · 1:20:33
Applied Intuition has spent the past decade building the software that powers intelligent machines, from passenger vehicles and trucks to defense systems, mining equipment, and…
Jul 20, 2026 · 28:08
As governments weigh new restrictions on frontier AI models, one question is becoming increasingly important: what role should open source play in the future of artificial…
Jul 17, 2026 · 25:47
Recorded live at the New Media Summit, Erik Torenberg sits down with Replit founder and CEO Amjad Masad to discuss founder-led storytelling, building in public, and the role of…
Jul 16, 2026 · 1:17:11
As part of our summer replay series, we're revisiting one of our most-discussed conversations from the past year. David Sacks joins Marc Andreessen, Ben Horowitz, and Erik…
Jul 15, 2026 · 1:05:18
As part of our summer replay series, we're revisiting one of our favorite conversations on the future of AI infrastructure. SemiAnalysis founder Dylan Patel joins Erin…
Jul 14, 2026 · 31:49
As part of our summer replay series, we're revisiting one of the standout conversations from Runtime, a16z's conference on AI infrastructure and the future of computing. Gavin…
Jul 13, 2026 · 37:20
Every blockchain today relies on replication techniques first developed in the 1980s by researchers who weren't thinking about cryptocurrencies at all. In this episode, Tim…
Jul 10, 2026 · 21:35
We're excited to share a special feed drop from The a16z Crypto Show. In the first episode of First Principles: The Scientific Roots of Blockchain Technology , Tim Roughgarden…
Jul 9, 2026 · 45:14
As part of our summer replay series, we're revisiting one of our favorite conversations from the past year. Mark Zuckerberg and Dr. Priscilla Chan join Ben Horowitz, Vineeta…
Jul 8, 2026 · 1:30:06
Adam Neumann joins Marc Andreessen, Ben Horowitz, and Erik Torenberg for a candid conversation about entrepreneurship, failure, and building Flow. Neumann reflects on his…
Jul 7, 2026 · 1:01:24
Seema Amble, Steven Sinofsky, and Elena Burger unpack one of the biggest questions facing enterprise software: what happens when AI agents become the primary users of software…
Jul 6, 2026 · 19:22
In this commencement address to Columbia University's Fu Foundation School of Engineering and Applied Science Class of 2015, Ben Horowitz challenges some of the most common…
Jul 3, 2026 · 42:51
Ben Horowitz is joined by Anne Neuberger, Raghu Raghuram, and Jen Kha to discuss a16z's expanding international strategy and the growing role technology plays in economic growth,…
Jul 2, 2026 · 41:15
What does it take to build a global mobility company from a country of just 1.3 million people? Markus Villig, founder and CEO of Bolt, joins the show to share how he scaled from…
Jul 1, 2026 · 1:15:58
Rick Rubin joins Marc Andreessen, Ben Horowitz, Anjney Midha, and Erik Torenberg to discuss creativity, artificial intelligence, and his book The Way of Code , which reimagines…
Jun 30, 2026 · 48:09
Yoko Li speaks with Luma's Head of Applied Research Matt Tancik and Phota Labs cofounder and CTO Zach Xia about how AI is changing creativity, photography, and the tools people…
Jun 29, 2026 · 1:04:31
Marc Andreessen joins CSIS's Navin Girishankar for a wide-ranging conversation on artificial intelligence, productivity growth, industrial policy, and America's technological…
Jun 26, 2026 · 34:09
Kevin Weil, the previous CPO & Vice President of Science at OpenAI, joins Speedrun to discuss the future of AI, scientific discovery, and startup building. After helping build…
Jun 25, 2026 · 1:04:10
Michael Malice sits down with Marc Andreessen to discuss artificial intelligence, technological progress, economic growth, and the future of human flourishing. Drawing on decades…
Jun 24, 2026 · 48:46
Anish Acharya speaks with Microsoft VP of Design John Maeda and Impeccable founder and CEO Paul Bakaus about how AI is changing the practice of design. The conversation explores…
Jun 23, 2026 · 53:54
Anish Acharya sits down with Josh Elman to discuss the future of consumer technology and Josh's decision to join a16z. Over the past two decades, Elman has helped shape some of…
Jun 22, 2026 · 1:04:54
Jake Paul and Geoff Woo join the podcast to announce Anti Fund’s new $100 million growth fund and discuss the evolution of their investment strategy. The conversation covers the…
Jun 19, 2026 · 41:10
Recorded live at the New Media Summit, Marc Andreessen, Ben Horowitz, Erik Torenberg, and Gaby Goldberg discuss how media, communication, and influence are changing in the…
Jun 17, 2026 · 48:57
Angela Strange and Gabriel Vásquez speak with Addi founder and CEO Santiago Suárez about building one of Latin America's largest financial platforms. What began as a buy now, pay…
Jun 16, 2026 · 29:24
Jack Altman joins Speedrun to discuss product-market fit, customer feedback, hiring, fundraising, and the realities of building an enduring company. Drawing on his experience…
Jun 15, 2026 · 42:56
Yoko Li and Justine Moore speak with Ideogram founder and CEO Mohammad Norouzi about image generation models, design workflows, and the evolving relationship between AI and…
Jun 12, 2026 · 27:51
Theo Jaffee speaks with Samo Burja, founder of Bismarck Analysis, about AI, industrial capacity, economic growth, and the institutions that shape civilization. The conversation…
Jun 11, 2026 · 50:05
Erin Price-Wright speaks with Alex Modon, cofounder and CEO at Unlimited Industries, and Davide Asnaghi, CEO at Diode Computers, about how AI is moving from software into the…
Jun 9, 2026 · 59:17
Wyatt Thomson of OpenAI speaks with economists Tyler Cowen and Alex Tabarrok about AI, labor markets, and the future of economic growth. The conversation explores one of the most…
Jun 8, 2026 · 1:01:18
Erik Torenberg speaks with tech analyst Benedict Evans about the current state of AI, what has changed over the past year, and which questions remain unanswered. The conversation…
Jun 6, 2026 · 49:44
Sarah Wang speaks with Exa cofounder and CEO Will Bryk about building search infrastructure for the AI era. The conversation covers Exa’s origins, why traditional search engines…
Jun 5, 2026 · 50:46
Martin Casado speaks with George Fraser, cofounder and CEO of Fivetran, about the future of data infrastructure in the age of AI. The conversation covers Fivetran’s merger with…
Jun 3, 2026 · 55:14
Theo Jaffee and Sophia Puccini speak with Balaji Srinivasan and Steven Glinert about the shifting balance of power between nations, networks, and technology. The conversation…
Jun 2, 2026 · 29:00
Theo Jaffee speaks with Steven Sinofsky about the next generation of personal computing and the growing role of AI-native hardware. The conversation covers NVIDIA’s entry into…
Jun 1, 2026 · 46:18
Anish Acharya and Olivia Moore speak with Pablo Palafox and Luis Paarup about the challenges of deploying AI agents in operationally complex industries. The conversation covers…
May 29, 2026 · 33:31
David George, General Partner at a16z, and David Clark, CIO at VenCap, discuss how AI is reshaping venture capital and the technology industry itself. They examine why today’s AI…
May 28, 2026 · 37:05
Angela Strange speaks with Dileep Thazhmon, founder and CEO of Jeeves, about building a global financial operating system for enterprises across Latin America using stablecoins…
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